Alrpax XR 1 (Alprazolam)

Description

Alprax XR — Extended Release Alprazolam Tablets

Indications

Alprax XR (Alprazolam XR) is indicated for the treatment of:

• Generalized Anxiety Disorder (GAD)

• Short-term relief of anxiety symptoms

• Anxiety associated with depression

• Panic disorder, with or without agoraphobia

* Take this medication only under the supervision of a registered healthcare professional.

Pharmacology

Alprazolam belongs to the triazole benzodiazepine class and acts as an anxiolytic with hypnotic and anticonvulsant properties. It works by enhancing the activity of Gamma-Aminobutyric Acid (GABA) at the benzodiazepine receptor complex, producing a dose-dependent CNS depressant effect — ranging from mild sedation to hypnosis.

Dosage & Administration

• Starting dose: 0.25–0.5 mg, three times daily

• Increase dose every 3–4 days by no more than 1 mg/day as needed

• Maximum dose: 4 mg/day (in some panic disorder cases, up to 10 mg/day under strict supervision)

Special instructions:

• Use the lowest effective dose for optimal benefit

• Gradually taper when discontinuing therapy (reduce by 0.5 mg every 3 days)

• Elderly patients or those with liver disease: Start at 0.25 mg two or three times daily, increase slowly if tolerated

• Alprazolam 1 mg XR: Administer once daily in the morning if on multiple doses; swallow tablets whole — do not chew, crush, or break

* Take only as advised by a registered doctor.

Drug Interactions

Alprax XR’s CNS-depressant effects may be enhanced when taken with:

• Other psychotropic medications

• Anticonvulsants

• Antihistamines

• Alcohol

• Oral contraceptives

Side Effects

Common side effects often appear at the start of therapy and typically decrease with continued use:

• Drowsiness, light-headedness

• Headache, confusion

• Depression, dry mouth, constipation

Pregnancy & Lactation

• Pregnancy Category D: Avoid during pregnancy

• Alprazolam is likely excreted in breast milk; breastfeeding is not recommended for mothers taking Alprax XR

Precautions & Warnings

• Risk of psychological and physical dependence; do not abruptly discontinue

• Administer with caution in patients with:

  • Liver or kidney disease

  • Sleep apnea

  • Chronic pulmonary insufficiency

Use in Special Populations

• Safety and effectiveness in individuals under 18 years of age have not been established

Overdose

Symptoms may include:

• Excessive sleepiness, confusion

• Impaired coordination, diminished reflexes

• Coma

Immediate supportive care and gastric lavage are recommended in case of overdose.

Therapeutic Class

Benzodiazepine sedatives

Storage

Store below 30°C, in a dry place away from light and moisture.
Keep out of reach of children.