Alprax XR 2mg (Alprazolam)

Description

Alprax XR — Extended Release Alprazolam Tablets

Indications

Alprax XR (Alprazolam Extended Release) is prescribed for the management of:

• Generalized Anxiety Disorder (GAD)

• Short-term relief from anxiety symptoms

• Anxiety associated with depressive disorders

• Panic disorder, with or without agoraphobia

Pharmacology

Alprazolam belongs to the triazole benzodiazepine class and works as an anxiolytic with hypnotic and anticonvulsant properties. It is believed to act through the GABA-benzodiazepine receptor complex, causing a dose-dependent CNS depressant effect ranging from mild sedation to deep hypnosis.

Dosage & Administration

• Initial dose: 0.25 mg – 0.5 mg three times daily

• Dose may be increased every 3–4 days by no more than 1 mg/day, depending on patient response

• Maximum daily dose: 4 mg/day
  (Some panic disorder patients may require up to 10 mg/day, only under careful clinical supervision)

• Elderly patients / liver impairment: Start with 0.25 mg two or three times daily, increase slowly if needed

• Alprazolam 1 mg XR: Taken once daily in the morning; swallow tablets whole (do not chew, crush, or break)

Drug Interactions

CNS depressant effects may increase when used together with:

• Other psychotropic medications

• Anticonvulsants

• Antihistamines

• Alcohol

• Oral contraceptives

Side Effects

Side effects commonly appear during the first few days of treatment and usually improve with continued use. Possible reactions include:

• Drowsiness, dizziness, light-headedness

• Headache, confusion

• Depression, dry mouth

• Constipation and general fatigue

Pregnancy & Lactation

• Pregnancy Category: D — not recommended during pregnancy

• Alprazolam may pass into breast milk, therefore breastfeeding is not advised for mothers taking Alprax XR

Precautions & Warnings

• Alprax XR may cause physical and psychological dependence

• Do not increase dose or stop therapy abruptly without medical supervision

• Use cautiously in patients with:

  • Liver or kidney disorders

  • Sleep apnea

  • Chronic pulmonary disease or respiratory problems

Use in Children

The safety and effectiveness of Alprax XR have not been established in patients under 18 years of age.

Overdose

Symptoms may include:

• Excessive sleepiness

• Confusion

• Poor coordination

• Decreased reflexes

• Coma

Immediate gastric lavage and supportive treatment are recommended in cases of overdose.

Therapeutic Class

Benzodiazepine Sedatives

Storage

Store below 30°C, protect from light and moisture.
Keep out of the reach of children.